Brain Ultimate TMS M-Series | FDA-Cleared TMS Device with 24/7 Deionized Water Cooling | Brain Ultimate
FDA CLEARED

Brain Ultimate TMS M-Series

The Most Advanced Affordable TMS System

Experience the only TMS device that uses pure deionized water for true 24/7 operation. While others rely on transformer oil and complex cooling systems, our proprietary design delivers continuous therapy with unmatched safety, simplicity, and no per-pulse fees.

FDA-Cleared for MDD, OCD & More
4 Treatment Protocols
Only Deionized Water Cooling
24/7 Continuous Operation
176 Peer-Reviewed Publications
5,000+ Study Participants
Trusted by 50+ Clinics Brain Ultimate TMS M-Series system in clinical setting showing stimulator, liquid-cooled coil, and patient chair

Brain Ultimate TMS by the Numbers

24/7
Continuous Operation
4
FDA-Cleared Protocols
3 min
Fastest Treatment (iTBS)
50+
Clinics Nationwide
176
Peer-Reviewed Studies
OVERVIEW

Introduction to Transcranial Magnetic Stimulation (TMS)

Transcranial Magnetic Stimulation (TMS) is a non-invasive method of brain stimulation. It works by directing a magnetic field pulse through the skull, where it induces electrical currents in the underlying brain tissue through Faraday's law of electromagnetic induction. TMS can both depolarize and hyperpolarize cortical neurons, influencing the immediate stimulation area and connected neural structures.

Beyond the direct stimulation site, TMS influences cortical and subcortical structures connected synaptically. The neurophysiological changes induced by repetitive TMS can persist beyond the stimulation period through long-term potentiation and depression mechanisms — making TMS an effective FDA-cleared treatment for Major Depressive Disorder, Obsessive-Compulsive Disorder, and additional indications.

The M-100 platform is backed by 96 published research studies, part of Brain Ultimate's comprehensive portfolio of 176 peer-reviewed publications involving over 5,000 participants across 150+ institutions, with a highest single-paper impact factor of 10.7.
CAPABILITIES

M-Series Ultimate TMS Device Features

Our TMS systems adhere to international safety standards with certifications including FDA, CE, CFDA, TGA, KFDA, and NMPA.

Advanced Safety Features

Comprehensive protection systems ensure patient and operator safety during every treatment session.

  • Dual-tier temperature protection: 41°C warning, 42°C auto-stop
  • Continuous monitoring of coolant level, temperature, and circulation
  • Enhanced patient data security with dongle authorization
  • Real-time system status indicators

Precision Positioning System

Advanced positioning technology ensures accurate and repeatable coil placement for optimal treatment outcomes.

  • 10-20 system positioning caps (S/M/L) for defined brain regions
  • Built-in coil position maps in QuickStim software
  • Flexible coil arm for precise adjustments
  • Compatible with neuronavigation systems

User-Friendly Software

QuickStim software provides comprehensive control with an intuitive touchscreen interface designed for clinical efficiency.

  • Effortless patient file creation and management
  • Built-in FDA-cleared protocols and custom protocol creation
  • Hot key access for frequently used protocols
  • Cloud connectivity from approved devices with QuickStim

Clinical Versatility

FDA-cleared for multiple conditions with four distinct treatment protocols to meet diverse patient needs.

  • Standard MDD Protocol (19 minutes)
  • Enhanced MDD Protocol (37 minutes)
  • iTBS Protocol (3 minutes)
  • OCD Protocol (18 minutes)

Practice Enhancement

Maximize clinic efficiency and patient throughput with no per-pulse or per-use fees.

  • True 24/7 operation with deionized water cooling
  • 20,000,000 pulse coil lifespan
  • Lightest coil on the market for operator comfort
  • Comprehensive installation, training, and ongoing support

Integration & Compatibility

Seamlessly integrates with existing clinical workflows and diagnostic equipment.

  • Compatible with EEG monitoring systems
  • MEP Module integration ($2,950 add-on)
  • Neuronavigation system compatible
  • Cloud-connected treatment management
PROPRIETARY TECHNOLOGY

The Only TMS with Pure Deionized Water Cooling

While other systems rely on transformer oil and complex cooling mechanisms, our proprietary technology uses only medical-grade deionized water for unmatched safety and simplicity.

Proprietary Liquid Cooling System — The Industry Standard-Setter

Pure Deionized Water

Unlike competitors using transformer oil, our system uses only medical-grade deionized water — eliminating the risks associated with oil-based cooling and ensuring a cleaner, safer treatment environment.

True 24/7 Operation

Continuous operation without overheating or performance degradation. Your clinic can treat patients all day without cooling breaks or system downtime.

Closed-Loop Safety

Sealed circulation system prevents leaks and contamination while maintaining optimal cooling efficiency with real-time temperature monitoring.

Exceptional Durability

Most clinics operate 2–3 years between coolant service. Resistant to electrolysis, corrosion, and blockages. Refill at 85% capacity — no complex maintenance required.

Brain Ultimate TMS proprietary deionized water liquid cooling system
TECHNICAL DETAILS

Comprehensive Specifications

FDA Clearance
K230735 (Sept 2023)
Cleared Indications
MDD, OCD, Anxious Depression, Smoking, Migraine
Protocols
4 FDA-Cleared
Cooling System
Proprietary Deionized Water
Operation Mode
24/7 Continuous
Software
QuickStim v3.3.8+
Frequency Range
0.1 – 100 Hz
Intensity Range
0 – 200% MT (software), up to 100% system output
Pulse Width
Biphasic (~100 µs)
Coil Type
Figure-8 Liquid Cooled
Coil Lifespan
20,000,000 pulses
Max Pulses/Session
Unlimited (24/7 capable)
Temperature Warning
41°C (flash + beep alert)
Temperature Auto-Stop
42°C (automatic shutdown)
Monitoring
Real-time temperature, coolant, status
Data Security
Dongle authorization + encrypted storage
Emergency Stop
Hardware and software
EMC Compliance
IEC 60601-1-2
Native Power
230VAC / 50Hz
US Configuration
Integrated step-down transformer (110V → 230V)
Max Input Power
3,500W
Minimum Site Capacity
5 kVA
Certifications
FDA, CE, CFDA, TGA, KFDA, NMPA
Display
Touch Screen
Connectivity
Ethernet, USB
Included Chair
Ergonomic Patient Chair
INTUITIVE CONTROL

QuickStim Software Platform

Comprehensive software designed for clinical efficiency with cloud connectivity from approved devices.

QuickStim patient management interface
QuickStim protocol creation screen
QuickStim treatment monitoring display
QuickStim reporting dashboard

Streamlined Clinical Workflow

QuickStim software simplifies every aspect of TMS treatment delivery, from patient intake to treatment completion and reporting.

  • Effortless Patient ManagementQuick patient file creation, comprehensive history tracking, and secure data storage with dongle authorization.
  • Built-in FDA-Cleared ProtocolsPre-loaded with all 4 FDA-cleared protocols plus custom protocol creation. Hot key access for frequent settings.
  • Cloud ConnectivityAccess patient data across devices with Brain Ultimate Cloud integration — from approved devices where QuickStim is installed.
  • Comprehensive ReportingGenerate treatment summaries, progress reports, and session documentation for clinical records.

Experience Our Technology Firsthand

Join the 50+ clinics nationwide that trust Brain Ultimate for reliable, affordable, and advanced TMS therapy — backed by 176 peer-reviewed studies and no per-pulse fees.

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